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Index > Protein center > Trpm2(Gene name) > Mouse
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  • Trpm2 (Gene name),
  • Transient receptor potential cation channel subfamily M member 2 (Protein name ),  TRPM2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Trpm2(Ltrpc2;Trpc7);
    Protein name:
    Transient receptor potential cation channel subfamily M member 2;
    Alternative:
    Transient receptor potential channel 7(TrpC7);Long transient receptor potential channel 2(LTrpC-2;LTrpC2);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Has ADP-ribose pyrophosphatase activity.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1507
    Sequence:
    50:
    MESLDRRRTG | SEQEEGFGVQ | SRRATDLGMV | PNLRRSNSSL | CKSRRFLCSF | 
    100:
    SSEKQENLSS | WIPENIKKKE | CVYFVESSKL | SDAGKVVCAC | GYTHEQHLEV | 
    150:
    AIKPHTFQGK | EWDPKKHVQE | MPTDAFGDIV | FTDLSQKVGK | YVRVSQDTPS | 
    200:
    SVIYQLMTQH | WGLDVPNLLI | SVTGGAKNFN | MKLRLKSIFR | RGLVKVAQTT | 
    250:
    GAWIITGGSH | TGVMKQVGEA | VRDFSLSSSC | KEGEVITIGV | ATWGTIHNRE | 
    300:
    GLIHPMGGFP | AEYMLDEEGQ | GNLTCLDSNH | SHFILVDDGT | HGQYGVEIPL | 
    350:
    RTKLEKFISE | QTKERGGVAI | KIPIVCVVLE | GGPGTLHTIY | NAINNGTPCV | 
    400:
    IVEGSGRVAD | VIAQVATLPV | SEITISLIQQ | KLSIFFQEMF | ETFTENQIVE | 
    450:
    WTKKIQDIVR | RRQLLTIFRE | GKDGQQDVDV | AILQALLKAS | RSQDHFGHEN | 
    500:
    WDHQLKLAVA | WNRVDIARSE | IFTDEWQWKP | ADLHPMMTAA | LISNKPEFVR | 
    550:
    LFLENGVRLK | EFVTWDTLLC | LYENLEPSCL | FHSKLQKVLA | EEQRLAYASA | 
    600:
    TPRLHMHHVA | QVLRELLGDS | TQLLYPRPRY | TDRPRLSMTV | PHIKLNVQGV | 
    650:
    SLRSLYKRST | GHVTFTIDPV | RDLLIWAVIQ | NHRELAGIIW | AQSQDCTAAA | 
    700:
    LACSKILKEL | SKEEEDTDSS | EEMLALADEF | EHRAIGVFTE | CYRKDEERAQ | 
    750:
    KLLVRVSEAW | GKTTCLQLAL | EAKDMKFVSH | GGIQAFLTKV | WWGQLCVDNG | 
    800:
    LWRIILCMLA | FPLLFTGFIS | FREKRLQALC | RPARVRAFFN | APVVIFHMNI | 
    850:
    LSYFAFLCLF | AYVLMVDFQP | SPSWCEYLIY | LWLFSLVCEE | TRQYLFYDPD | 
    900:
    GCGLMKMASL | YFSDFWNKLD | VGAILLFIVG | LTCRLIPATL | YPGRIILSLD | 
    950:
    FIMFCLRLMH | IFTISKTLGP | KIIIVKRMMK | DVFFFLFLLA | VWVVSFGVAK | 
    1000:
    QAILIHNESR | VDWIFRGVVY | HSYLTIFGQI | PTYIDGVNFS | MDQCSPNGTD | 
    1050:
    PYKPKCPESD | WTGQAPAFPE | WLTVTLLCLY | LLFANILLLN | LLIAMFNYTF | 
    1100:
    QEVQEHTDQI | WKFQRHDLIE | EYHGRPPAPP | PLILLSHLQL | LIKRIVLKIP | 
    1150:
    AKRHKQLKNK | LEKNEETALL | SWELYLKENY | LQNQQYQQKQ | RPEQKIQDIS | 
    1200:
    EKVDTMVDLL | DMDQVKRSGS | TEQRLASLEE | QVTQVTRALH | WIVTTLKDSG | 
    1250:
    FGSGAGALTL | APQRAFDEPD | AELSIRRKVE | EPGDGYHVSA | RHLLYPNARI | 
    1300:
    MRFPVPNEKV | PWAAEFLIYD | PPFYTAEKDV | ALTDPVGDTA | EPLSKISYNV | 
    1350:
    VDGPTDRRSF | HGVYVVEYGF | PLNPMGRTGL | RGRGSLSWFG | PNHTLQPVVT | 
    1400:
    RWKRNQGGAI | CRKSVRKMLE | VLVMKLPRSE | HWALPGGSRE | PGEMLPRKLK | 
    1450:
    RVLRQEFWVA | FETLLMQGTE | VYKGYVDDPR | NTDNAWIETV | AVSIHFQDQN | 
    1500:
    DMELKRLEEN | LHTHDPKELT | RDLKLSTEWQ | VVDRRIPLYA | NHKTILQKVA | 
    1507:
    SLFGAHF
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Transient receptor potential cation channel subfamily M member 2
    Cat.:
    E12145h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Transient receptor potential cation channel subfamily M member 2
    Cat.:
    E12145m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Transient receptor potential cation channel subfamily M member 2
    Cat.:
    U12145m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Transient receptor potential cation channel subfamily M member 2
    Cat.:
    U12145h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Transient receptor potential cation channel subfamily M member 2
    Cat.:
    P12145Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Transient receptor potential cation channel subfamily M member 2
    Cat.:
    P12145Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Transient receptor potential cation channel subfamily M member 2
    Monoclonal Antibody for Mouse Transient receptor potential cation channel subfamily M member 2
    Protein for Mouse Transient receptor potential cation channel subfamily M member 2
    Protein for Mouse Transient receptor potential cation channel subfamily M member 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      Kashuba V.
      Submitted (2001-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
    2. 2.
      "LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death."
      Hara Y. , Wakamori M. , Ishii M. , Maeno E. , Nishida M. , Yoshida T. , Yamada H. , Shimizu S. , Mori E. , Kudoh J. , Shimizu N. , Kurose H. , Okada Y. , Imoto K. , Mori Y.
      Mol. Cell9:163-173(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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